Comprehensive and current, this one-of-a-kind resource offers students and practitioners an ideal reference in therapeutic drug decision-making. . . Melmon and Morrelli's Clinical Pharmacology builds the necessary links among scientific principles, fact-based evidence, and clinical experience. Designed to aid physicians at all levels in improving the quality of treatment and providing optimal pharmotherapeutic plans for patients, this resource outlines a problem-based approach to drug therapy that emphasizes the rationale behind it.. . Fully updated to keep pace with advances in medicine, Melmon and Morrelli's Clinical Pharmacology is 75% new and substantially revised, with new coverage of antimicrobials, drug kinetics and dynamics, drug interactions, and more. With chapters written by leading international experts in many therapeutic fields, this resource provides: . . *In-depth discussions of the principles of therapeutic choice that apply across multiple types of treatment. *Chapters on drug treatments for pulmonary, infectious, cardiovascular, psychiatric, hematologic diseases, and other areas frequently encountered in internal medicine. *Coverage of special-case scenarios, such as stages of life and patients with various drug needs.